Selected Publications

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2020

Single-cell RNA counting at allele and isoform resolution using Smart-seq3
Michael Hagemann-Jensen, Christoph Ziegenhain, Ping Chen, Daniel Ramsköld, Gert-Jan Hendriks, Anton J. M. Larsson, Omid R. Faridani & Rickard Sandberg
Nature Biotechnology 2020. https://doi.org/10.1038/s41587-020-0497-0

2019

Genomic encoding of transcriptional burst kinetics
Larsson, AJM; Johnsson, P; Hagemann-Jensen, M; Hartmanis, L; Faridani, OR; Reinius, B; Segerstolpe, Å; Rivera, CM; Ren, B; Sandberg, R
Nature, 2019, 251-254.

NASC-seq monitors RNA synthesis in single cells
Hendriks, GJ; Jung, LA; Larsson, AJM; Lidschreiber, M; Andersson Forsman, O; Lidschreiber, K; Cramer, P; Sandberg, R
Nature communications, 2019, 3138-.

X-chromosome upregulation is driven by increased burst frequency
Larsson, AJM; Coucoravas, C; Sandberg, R; Reinius, B
Nature Structural & Molecular Biology, 2019, 963-969.

2018

Computational correction of index switching in multiplexed sequencing libraries
Larsson, AJM; Stanley, G; Sinha, R; Weissman, IL; Sandberg, R
Nature methods, 2018, 305-307.

Identification of spatial expression trends in single-cell gene expression data
Edsgärd, D; Johnsson, P; Sandberg, R
Nature methods, 2018, 339-342.

2016

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq
Reinius, B; Mold, JE; Ramsköld, D; Deng, Q; Johnsson, P; Michaëlsson, J; Frisén, J; Sandberg, R
Nature genetics, 2016, 1430-1435.

Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq
Cadwell, CR; Palasantza, A; Jiang, X; Berens, P; Deng, Q; Yilmaz, M; Reimer, J; Shen, S; Bethge, M; Tolias, KF; Sandberg, R*; Tolias, AS*
Nature biotechnology, 2016, 199-203.

scphaser: haplotype inference using single-cell RNA-seq data
Edsgärd, D; Reinius, B; Sandberg, R
Bioinformatics (Oxford, England), 2016, 3038-40.

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos
Petropoulos, S; Edsgärd, D; Reinius, B; Deng, Q; Panula, SP; Codeluppi, S; Plaza Reyes, A; Linnarsson, S; Sandberg, R*; Lanner, F*
Cell, 2016, 1012-26.

Single-cell sequencing of the small-RNA transcriptome
Faridani, OR; Abdullayev, I; Hagemann-Jensen, M; Schell, JP; Lanner, F; Sandberg, R
Nature biotechnology, 2016, 1264-1266.

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
Segerstolpe, Å; Palasantza, A; Eliasson, P; Andersson, EM; Andréasson, AC; Sun, X; Picelli, S; Sabirsh, A; Clausen, M; Bjursell, MK; Smith, DM; Kasper, M; Ämmälä, C; Sandberg, R
Cell metabolism, 2016, 593-607.

2015

Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation
Reinius, B; Sandberg, R
Nature reviews. Genetics, 2015, 653-64.

2014

Entering the era of single-cell transcriptomics in biology and medicine
Sandberg, R
Nature Methods, 2014, 22-4.

Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells
Deng, Q; Ramsköld, D; Reinius, B; Sandberg, R
Science (New York, N.Y.), 2014, 193-6.

Tn5 transposase and tagmentation procedures for massively scaled sequencing projects
Picelli, S; Björklund, AK; Reinius, B; Sagasser, S; Winberg, G; Sandberg, R
Genome research, 2014, 2033-40.

2013

Smart-seq2 for sensitive full-length transcriptome profiling in single cells
Picelli, S; Björklund, ÅK; Faridani, OR; Sagasser, S; Winberg, G; Sandberg, R
Nature methods, 2013, 1096-8.

2012

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
Ramsköld, D; Luo, S; Wang, YC; Li, R; Deng, Q; Faridani, OR; Daniels, GA; Khrebtukova, I; Loring, JF; Laurent, LC; Schroth, GP; Sandberg, R
Nature biotechnology, 2012, 777-82.

2008

Alternative isoform regulation in human tissue transcriptomes
Wang, ET; Sandberg, R; Luo, SJ; Khrebtukova, I; Zhang, L; Mayr, C; Kingsmore, SF; Schroth, GP; Burge, CB
NATURE, 2008, 470-6.

Proliferating cells express mRNAs with shortened 3 ' untranslated regions and fewer microRNA target sites
Sandberg, R; Neilson, JR; Sarma, A; Sharp, PA; Burge, CB
SCIENCE, 2008, 1643-7.


© 2020 Sandberg lab at Karolinska Institutet, Stockholm, Sweden.